一、招聘职位：博士后-衰老和癌症计算表观遗传学方向

中国科学院上海营养与健康研究所Andrew Teschendorff研究员领导的计算系统表观遗传学研究组诚招博士后。研究组旨在研究和阐明表观遗传变化，特别是DNA甲基化改变在衰老和癌症易感性中的作用。该博士后职位的具体职责可能包括：(1) 开发用于DNA甲基化数据的细胞类型解卷积的新计算策略，(2) 开发用于从多模态单细胞组学数据预测癌症风险的新计算策略，(3) 开发用于构建细胞类型特异性表观遗传学和转录组学时钟的新计算策略。研究组在许多现有方法的开发和发展上起到了先锋作用，Andrew Teschendorff研究员在2023年获得了享有盛誉的Clarivate高被引研究人员奖。研究组与美国、中国和欧洲的研究小组有广泛的合作，因此，这份工作对于最近获得博士学位的人来说，是发表高影响力论文并在计算生物学领域发展国际学术生涯和建立声誉的绝佳机会。关于研究组研究领域和过去发表的论文，更多细节可以参阅研究组网站https://aet21.github.io

二、应聘条件：

拥有统计组学/生物信息学/计算生物学或其他密切相关的计算/数学学科的博士学位。在R/BioC和Python方面拥有出色的编程技能。熟练使用Linux操作系统。

该职位预计从2025年1月开始，最初工作期为2年，如表现出色可适当延长工作年限。初始年薪约为50万元人民币，另外包括其它福利，例如餐食和住宿补贴等。

三、报名方式

有意应聘者，请将简历和求职信发送至andrew@sinh.ac.cn和aeteschendorff21@outlook.com

该职位招聘人数共计2名，招满为止。

Postdoctoral Position in Computational Epigenomics of Aging and Cancer

An opportunity has arisen to join the Computational Systems Epigenomics lab, led by Professor Andrew Teschendorff, based at the Shanghai Institute of Nutrition and Health, which is part of the Chinese Academy of Sciences. Our lab has an interest in elucidating the role of epigenetic changes, notably DNA methylation alterations, in aging and cancer predisposition. The specific role of the postdoc position may include (1) to develop novel computational strategies for cell-type deconvolution of DNA methylation data, (2) develop novel computational strategies for cancer risk prediction from multi-modal single-cell omic data, and (3) develop novel computational strategies for building cell-type specific epigenetic and transcriptomic clocks. Our lab has pioneered many of the existing methods, in 2023 receiving a prestigious Clarivate Highly Cited Researcher Award. We collaborate extensively with leading research groups in the US, China and Europe. Thus, the job is an excellent opportunity for a recent PhD graduate to publish high impact papers and grow their international academic career and reputation in Computational Biology. More details about our research interests and past publications can be found here: https://aet21.github.io

Job requirements：

A PhD in Statistical Omics/Bioinformatics/Computational Biology or closely related computational/mathematical discipline. Excellent programming skills in R/BioC and Python. Proficiency in using linux OS.

The post starts in January 2025 and is initially for 2 years, but can be extended for additional years upon satisfactory performance. Initial annual salaries will be on the scale of ~ RMB 500,000. Job comes with additional benefits, including subsidy for meals and accommodation.

If interested, please send a CV and cover letter to andrew@sinh.ac.cn and aeteschendorff21@outlook.com

Positions (of which there are two) will be filled on a first-come first-serve basis.

信息来源于网络，如有变更请以原发布者为准。